In which of the following scenarios would NIMS be most useful?

NIMS would be most useful in a scenario involving a natural disaster impacting multiple jurisdictions because this framework is specifically designed to enhance coordination and collaboration among various agencies, organizations, and jurisdictions during complex incidents. When a disaster spans beyond a single area's resources or emergency response capabilities, effective communication and mutual aid become crucial.

NIMS provides standardized processes and protocols that facilitate the coordination of resources and information sharing across different responding entities—such as local, state, tribal, and federal organizations—ensuring a unified approach to managing the incident. The complexity and scale of a multi-jurisdictional disaster necessitate the use of NIMS to establish clear command structures, resource management systems, and effective incident action planning, which are essential for efficient emergency response and recovery efforts.